Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI3B1), TrueMAB

Applications

• Western Blot (WB): Tested dilution 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The CD4 antigen plays a key role in the recognition of MHC class II molecules and serves as a co-receptor for HIV. It is primarily expressed in T helper cells but can also be found in monocytes, macrophages, and dendritic cells.
At the tissue level, CD4 is detected in thymus, lymph nodes, tonsils, spleen, and certain non-lymphoid tissues.
CD4 participates in early T-cell activation via association with the T-cell receptor complex and Lck kinase and may mediate neuronal damage in immune-related CNS disorders.
Multiple alternatively spliced transcripts have been identified for this gene (RefSeq, July 2017).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.