Thermo Fisher Scientific IL-12 p70 Polyclonal Antibody
돼지 IL-12 p70에 특이적인 goat polyclonal antibody로, Western blot 및 neutralization assay에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 순도를 제공. 인간 및 생쥐 IL-12와 낮은 교차 반응성. 연구용으로 면역 반응 및 사이토카인 분석에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.1 µg/mL
Neutralization (Neu)
- Tested Dilution: 0.01–0.04 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Pig |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CHO-derived recombinant porcine IL-12 p35/p40 heterodimer (Ile23–Asn324, p40; Arg26–Ser222, p35) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607646 |
Product Specific Information
- In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human IL-12 and <5% cross-reactivity with recombinant mouse IL-12 observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
- Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).
Target Information
IL-12 p70 (Interleukin-12) is a cytokine essential for immune responses to infection and cancer. It is produced by dendritic cells, macrophages, and B cells in response to pathogens and tumor cells.
IL-12 p70 promotes interferon-gamma production, T cell activation, and NK cell proliferation.
It is a potential therapeutic target for infectious diseases, autoimmune disorders, and cancer due to its role in enhancing immune responses and modulating inflammation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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