Thermo Fisher Scientific Rab3-GAP1 Polyclonal Antibody
Rab3-GAP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 4°C에서 보관하며, 신경 발달 관련 연구에 유용한 고품질 연구용 항체입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 350 and 400 of Human RAB3 GTPase activating protein subunit 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
RAB3GAP1 is a 981 amino acid protein belonging to the Rab3-GAP catalytic subunit family. Rab3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP and is essential for normal eye and brain development.
Defects in Rab3 GAP p130 cause Warburg micro syndrome 1 (WARBM1), a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system, and microgenitalia.
Rab3 GAP p130 may participate in neurodevelopmental processes such as proliferation, migration, and differentiation before synapse formation, as well as non-synaptic vesicular release of neurotransmitters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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