Thermo Fisher Scientific APRIL Polyclonal Antibody
APRIL 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%) 제품. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 151–200 of Human APRIL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803152 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
Members of the TNF superfamily regulate immune responses and induce apoptosis. APRIL (A Proliferation-Inducing Ligand), also known as TALL2 or TRDL1a, is a novel member of this family identified in human and mouse. Two receptors for APRIL, TACI and BCMA, have been characterized. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death. APRIL and its related ligand BlyS, along with their receptors BCMA and TACI, are implicated in autoimmune diseases and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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