Thermo Fisher Scientific NOS1AP Monoclonal Antibody (OTI10F8), TrueMAB
인간 NOS1AP 단백질(aa 1-196)에 특이적인 Mouse IgG2a 단일클론 항체. Western blot에 최적화되어 있으며, 동결건조 형태로 제공. 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10F8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–196 of human NOS1AP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The NOS1AP gene encodes a cytosolic protein that binds to neuronal nitric oxide synthase (nNOS).
It contains:
- A C-terminal PDZ-binding domain mediating interaction with nNOS
- An N-terminal phosphotyrosine binding (PTB) domain that binds Dexras1
This protein functions as an adapter linking nNOS to targets such as Dexras1 and synapsins.
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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