Thermo Fisher Scientific TBL1XR1 Monoclonal Antibody (OTI2A8), TrueMAB
TBL1XR1 단백질을 인식하는 Mouse monoclonal antibody로, Western Blot에 적합. Human, Mouse, Rat 종에 반응하며, IgG1 아이소타입. 동결건조 형태로 제공되며, PBS buffer와 8% trehalose 포함. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A8 |
| Immunogen | Full length human recombinant protein of human TBL1XR1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Chromatin organization plays a key role in transcription regulation in eukaryotic cells.
N-CoR and SMRT are nuclear receptor corepressors involved in transcriptional repression pathways. These complexes recruit histone deacetylases (HDACs), particularly HDAC3, to establish repressive chromatin structures.
TBLR1, a WD-40 repeat protein, associates with N-CoR and SMRT complexes and is considered a core component, though its precise role remains under investigation.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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