Thermo Fisher Scientific KPNB1 Monoclonal Antibody (OTI10D3), TrueMAB
Thermo Fisher Scientific의 KPNB1 Monoclonal Antibody (OTI10D3)은 Human, Mouse, Rat에 반응하며 Western blot에 적합합니다. Human KPNB1 단백질(aa 1-200)을 항원으로 제작된 Mouse IgG2a 단일클론 항체입니다. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다.
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- CF811700
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI10D3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–200 of human KPNB1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform desalting again using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Nucleocytoplasmic transport is a signal- and energy-dependent process occurring through nuclear pore complexes. Proteins with a nuclear localization signal (NLS) require the importin alpha and beta heterodimer (karyopherins) for transport. Importin alpha binds NLS-containing cargo, while importin beta facilitates docking at the nuclear pore complex. In the presence of nucleoside triphosphates and Ran GTPase, the complex translocates through the pore, dissociates, and importin alpha enters the nucleoplasm with its cargo. Importin beta remains at the pore. Interactions between importin beta and FG repeats of nucleoporins are essential for translocation. The KPNB1 gene encodes a member of the importin beta family.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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