Thermo Fisher Scientific LAMP5 (Late Endosomes Marker) Monoclonal Antibody (LAMP5/7642)

Applications

Tested Dilution

Publications

Western Blot (WB)

2-4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2, kappa

Class

Monoclonal

Type

Antibody

Clone

LAMP5/7642

Immunogen

Recombinant full-length human LAMP5 protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LAMP5 (BAD-LAMP),uniProtId:Q9UJQ1-1,ncbiNodeId:9606,antigenRange:1-280,antigenLength:280,antigenImageFileName:24141-MSM2-P0_LAMP5_BAD-LAMP_Q9UJQ1-1_House_mouse.svg,antigenImageFileNamePDP:24141-MSM2-P0_LAMP5_BAD-LAMP_Q9UJQ1-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

Protein A/G

Storage buffer

PBS with 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Positive Control:Human brain.

Cellular Location: Cell Surface. Lysosome.

Target Information

Lysosome-associated membrane protein 5 (LAMP5) is a member of the LAMP family. LAMP5 differs from other LAMP family members in that its expression is more restricted and is referred to as brain and dendritic cell-associated LAMP-like molecule (BAD-LAMP). In humans, BAD-LAMP is expressed in post-natal neurons and non-activated plasmacytoid dendritic cells. Expression in neurons is localized to intracellular vesicles distributed in specific microdomains along neurites and may play a role in endocytosis. BAD-LAMP is localized to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) of plasmacytoid dendritic cells and is lost upon TLR activation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.