Thermo Fisher Scientific LRBA Polyclonal Antibody
LRBA 단백질을 인식하는 Thermo Fisher의 토끼 폴리클로날 항체. Western blot 및 Immunoprecipitation에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 4°C 보관, 1년 권장 유효기간. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1125 to 1175 of human LPS-Responsive Vesicle Trafficking, Beach and Anchor Containing (LRBA, UniProt ID: P50851-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
The protein encoded by this gene belongs to the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in guiding intracellular vesicles to activated receptor complexes, aiding in the secretion or membrane deposition of immune effector molecules.
Defects in this gene are associated with common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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