Thermo Fisher Scientific RED Polyclonal Antibody
Thermo Fisher Scientific RED Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 반응하며 Western blot과 ELISA에 적합합니다. Rabbit IgG 폴리클로날 항체로, 액상 형태이며 -20°C에서 보관합니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA5120336
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:200–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–280 of human IK (NP_006074.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.34 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2913908 |
Product Specific Information
- Positive test controls: A-549, HeLa, LO2, Mouse brain, Mouse testis, Rat kidney
- Localization: Nucleus
Immunogen sequence:
MPERDSEPFS NPLAPDGHDV DDPHSFHQSK LTNEDFRKLL MTPRAAPTSA PPSKSRHHEM PREYNEDEDP AARRRKKKSY YAKLRQQEIE RERELAEKYR DRAKERRDGV NKDYEETELI STTANYRAVG PTAEADKSAA EKRRQLIQES KFLGGDMEHT HLVKGLDFAL LQKVRAEIAS KEKEEEELME KPQKETKKDE DPENKIEFKT RLGRNVYRML FKSKAYERNE LFLPGRMAYV VDLDDEYADT DIPTTLIRSK ADCPTMEAQT TLTTNDIVIS
Target Information
Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family.
IMP-3 is expressed during embryogenesis and in certain malignancies, including malignant melanoma. It is not expressed in benign nevi, even when dysplastic features are present, and shows higher expression in melanomas and metastatic melanomas compared to thin melanomas. IMP-3 may play a role in tumor progression and regulation of melanoma biological behavior.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-120336_RED_Q13123-1_Rabbit.svg, PA5-120336_RED_Q13123-1_Rabbit_PDP.jpeg)
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