
Thermo Fisher Scientific PSMD10 Polyclonal Antibody
Thermo Fisher Scientific의 PSMD10 Polyclonal Antibody는 인간 PSMD10 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot 및 Immunocytochemistry에 적합하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 다양한 세포주에 대한 높은 반응성을 보입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 12–226 of Human PSMD10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.26 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547312 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
- Predicted reactivity: Mouse (95%), Rat (94%), Chicken (81%), Rhesus Monkey (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator.
- The 20S core consists of 4 rings of 28 non-identical subunits (two α-rings and two β-rings).
- The 19S regulator includes a base (6 ATPase subunits and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and are responsible for ATP/ubiquitin-dependent peptide cleavage in a non-lysosomal pathway.
The PSMD10 gene encodes a non-ATPase subunit of the 19S regulator, with two transcript variants producing different isoforms. Pseudogenes are identified on chromosomes 3 and 20.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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