Thermo Fisher Scientific PSMD10 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
• Predicted reactivity: Mouse (95%), Rat (94%), Chicken (81%), Rhesus Monkey (100%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

The 26S proteasome is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator.

• The 20S core consists of 4 rings of 28 non-identical subunits (two α-rings and two β-rings).
• The 19S regulator includes a base (6 ATPase subunits and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits).
  Proteasomes are abundant in eukaryotic cells and are responsible for ATP/ubiquitin-dependent peptide cleavage in a non-lysosomal pathway.
  The PSMD10 gene encodes a non-ATPase subunit of the 19S regulator, with two transcript variants producing different isoforms. Pseudogenes are identified on chromosomes 3 and 20.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.