Thermo Fisher Scientific PKD2 Polyclonal Antibody
PKD2 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 IHC(파라핀) 실험에 적합합니다. 인간에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to a region within amino acids 724–968 of Human Polycystin 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2547308 |
Product Specific Information
- Recommended positive control: U87-MG
- Predicted reactivity: Mouse (92%), Rat (94%), Zebrafish (86%), Pig (98%), Chicken (92%), Bovine (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains and cytoplasmic N- and C-termini. It may function as an integral membrane protein involved in cell-cell or matrix interactions, and plays a role in renal tubular development, morphology, and function. It may also modulate intracellular calcium homeostasis and other signal transduction pathways. The protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene are associated with autosomal dominant polycystic kidney disease.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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