Thermo Fisher Scientific DAO Polyclonal Antibody
Rabbit polyclonal antibody against human DAO protein. Validated for WB and IHC(P) applications. Detects endogenous DAO levels. Suitable for human, mouse, and rat samples. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DAO (Accession P14920), corresponding to amino acid residues V285–E335 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852113 |
Product Specific Information
Antibody detects endogenous levels of total DAO.
Target Information
This gene encodes the peroxisomal enzyme D-amino acid oxidase (DAO). The enzyme is a flavoprotein that uses flavin adenine dinucleotide (FAD) as its prosthetic group. It acts on various D-amino acids but is inactive on naturally occurring L-amino acids. DAO may function as a detoxifying enzyme removing D-amino acids accumulated during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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