Thermo Fisher Scientific GLRX Polyclonal Antibody
GLRX 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot 및 IHC(Paraffin) 실험에 적합. Human, Mouse, Rat 반응성. 1 mg/mL 농도의 액상 시약으로, -20°C 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GLRX (Accession P35754), corresponding to amino acid residues M1–E44 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852114 |
Product Specific Information
Antibody detects endogenous levels of total Glutaredoxin 1.
Target Information
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs are part of the glutaredoxin system, comprising NADPH, GSH, and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH.
Initially discovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase reactions via two redox-active cysteine residues.
The active sequence (Cys-Pro-Tyr-Cys) is conserved across species. This 12-kDa dithiol protein plays a role in reducing mixed disulfides in cells exposed to oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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