Thermo Fisher Scientific Thrombomodulin Monoclonal Antibody (QBEND/40)

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:10-1:50

-

Immunohistochemistry (Frozen) (IHC (F))

1:10-1:100

-

Flow Cytometry (Flow)

Neat

-

Product Specifications

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

QBEND/40

Immunogen

Human endothelium (thrombomodulin) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Thrombomodulin (CD141),uniProtId:P07204-1,ncbiNodeId:9606,antigenRange:1-575,antigenLength:575,antigenImageFileName:MA5-16928_Thrombomodulin_CD141_P07204-1_House_mouse.svg,antigenImageFileNamePDP:MA5-16928_Thrombomodulin_CD141_P07204-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2538405

Product Specific Information

Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for the staining of paraffin sections. A suggested positive control for immunohistochemical applications is lymph node. For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

Target Information

Thrombomodulin (TM) is also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112. Thrombomodulin contains six repeated domains homologous with epidermal growth factor (EGF) and an amino terminal domain homologous to lectin-like protein. Through its accelerated activation of protein C, synthesis of TM is one of several mechanisms important in maintaining thrombo-resistance and thus reducing clot formation on the surface of the endothelial cells. Immunohistochemical staining of formalin-fixed tissue for TM has been used for the study of a variety of vascular tumors, meningiomas and choriocarcinomas.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.