Thermo Fisher Scientific Phospho-G3BP1 (Ser149) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human G3BP1(Accession Q13283), corresponding to amino acid residues around phosphorylated Ser149. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:G3BP1,uniProtId:Q13283-1,ncbiNodeId:9606,antigenRange:149,antigenLength:466,antigenImageFileName:PA5-106176_G3BP1_Q13283-1_Rabbit.svg,antigenImageFileNamePDP:PA5-106176_G3BP1_Q13283-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2817574

Product Specific Information

Antibody detects endogenous levels of G3BP-1 only when phosphorylated at Ser149.

Target Information

This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3`-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.