Thermo Fisher Scientific Angiogenin Polyclonal Antibody
Angiogenin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB 및 IHC(P) 실험에 적합하며 인간, 마우스, 랫트에 반응. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, 연구용 전용.
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Thermo Fisher Scientific Angiogenin Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human ANG (Accession P03950), corresponding to amino acid residues H32–E82 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851826 |
Product Specific Information
Antibody detects endogenous levels of total Angiogenin.
Target Information
Angiogenin (ANG or ANG I) plays a key role in neovascularization and new blood vessel formation. It is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that inhibits protein synthesis by hydrolyzing cellular tRNAs.
ANG interacts with endothelial cell-surface actin, influencing cytoskeletal organization. It is implicated in solid tumor development, and its antagonists can inhibit tumor growth.
Defects in ANG are associated with susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin serves as a genetic link between ALS and Parkinson’s disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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