Thermo Fisher Scientific CDK6 Polyclonal Antibody
CDK6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 IHC(P)에서 검증된 고특이성 항체로, 인간·생쥐·랫드 시료에 반응. 액상 형태로 1 mg/mL 농도, PBS/glycerol buffer에 보관. 세포주기 연구용으로 적합.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CDK6 (Accession Q00534), corresponding to amino acid residues M1–Q48 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851825 |
Product Specific Information
Antibody detects endogenous levels of total CDK6.
Target Information
CDK6 functions as a cell-cycle initiator protein. This protein is coexpressed and copurified with Cyclin D1 and plays a critical role in cell cycle progression. The prototype member of this family, p34cdc2, and related protein cdk2 function late in the cycle, while cdk4 and cdk6 are involved in G1 to S phase transition.
CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in the gene result in microcephaly 12, primary, autosomal recessive (MCPH12).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-102420_CDK6_Q00534-1_Rabbit.svg, PA5-102420_CDK6_Q00534-1_Rabbit_PDP.jpeg)
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