Thermo Fisher Scientific Collagen V Polyclonal Antibody
Collagen V 단백질을 검출하기 위한 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 시료에 반응하며 WB, IHC, ICC/IF에 사용 가능. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, PBS/glycerol buffer로 안정적 보관 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COL5A1 (Accession P20908), corresponding to amino acid residues E305–L355 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851821 |
Product Specific Information
Antibody detects endogenous levels of total Collagen V alpha 1.
Target Information
COL5A1 encodes an alpha chain for one of the low-abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. COL5A1 product is closely related to type XI collagen, and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations. Mutations in this gene are associated with Ehlers-Danlos syndrome types I and II.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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