Thermo Fisher Scientific MMP3 Monoclonal Antibody (1B4)
인간 MMP3 단백질을 인식하는 Mouse IgG1 단일클론 항체입니다. Western blot, IHC, ELISA에 적합하며, 단백질 A/G 정제 및 PBS 버퍼에 0.08% sodium azide 포함. 조직 수복 및 리모델링 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 1–5 µg/mL |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B4 |
| Immunogen | Synthetic peptide derived from the C-terminus of the human MMP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.54 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | 0.08% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1076939 |
Product Specific Information
A suggested positive control for this product is esophageal or gastric tissues.
Target Information
MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form and activated by extracellular proteinase cleavage. MMP3 binds to zinc and calcium ions and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It plays a role in wound repair and tissue remodeling. Mutations in the gene may result in coronary heart disease 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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