Thermo Fisher Scientific Acetyl-alpha Tubulin (Lys40) Monoclonal Antibody (6-11B-1)
Acetylated α-tubulin(Lys40)을 인식하는 mouse monoclonal antibody로, 인간·마우스·랫 등 다양한 종에 반응합니다. Western blot, ICC/IF, IHC 등 다양한 응용에 사용 가능하며, 단백질 A로 정제된 0.5 mg/mL 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications 및 Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | View 10 publications |
| Immunohistochemistry (IHC) | – | View 23 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | – | View 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | – | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1–3 µg/mL | View 36 publications |
| Flow Cytometry (Flow) | Assay-dependent | – |
| Miscellaneous PubMed (Misc) | – | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat, Sea urchin |
| Published Species | Algae, Arthropod, Chicken, Dog, Flatworm, Human, Mollusc, Mouse, Protozoa, Rat, Zebrafish |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6-11B-1 |
| Immunogen | Acetylated alpha-tubulin from the axoneme of sea urchin sperm flagella |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.1% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2533073 |
Product Specific Information
This antibody reacts with the ~55 kDa acetylated form of alpha-tubulin. It shows reactivity with human, mouse, and rat, confirmed in NIH3T3 and HeLa cells.
Target Information
Alpha Tubulin is a component of the alpha-beta tubulin heterodimer, the fundamental unit of microtubules. These filaments are essential for cellular structure, intracellular transport, and mitosis. Microtubules are present in nearly all eukaryotic cells and are composed of highly conserved alpha and beta tubulin subunits. The alpha-tubulin gene shares high similarity with the mouse and rat Tuba1 gene, with expression predominantly in morphologically differentiated neuronal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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