Thermo Fisher Scientific IFITM3 Recombinant Rabbit Monoclonal Antibody (JU73-02)
IFITM3 단백질을 표적하는 Thermo Fisher의 재조합 토끼 단일클론 항체로, 높은 특이성과 민감도를 제공. WB, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합. 동물 유래 성분이 없는 포뮬레이션으로 로트 간 일관성 우수. 연구용으로만 사용 가능.
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Thermo Fisher Scientific IFITM3 Recombinant Rabbit Monoclonal Antibody (JU73-02)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JU73-02 |
| Immunogen | Synthetic peptide within Human Fragilis aa 1–50 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2810074 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages include:
- Enhanced specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
IFITM3 (Interferon Induced Transmembrane Protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein belonging to the IFITM family. IFITM proteins are induced by type I and type II interferons and contain multiple IFN-stimulated response elements (ISREs) in their promoters.
They play roles in:
- Cellular anti-proliferative activities
- Homotypic cell adhesion functions
- Potential involvement in carcinogenesis due to upregulation in cancer cells
IFITM3 is a 133-amino-acid membrane protein induced by IFN-alpha and IFN-gamma, regulated by TEF-1, Brg-1, and Sp1.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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