Thermo Fisher Scientific Lyn Monoclonal Antibody (R.677.10)
Lyn 단백질에 특이적인 Rabbit 모노클로날 항체로, WB, IHC, ICC/IF, IP 등 다양한 응용 가능. 인간, 마우스, 비인간 영장류, 랫트 반응성. 고순도 친화 크로마토그래피 정제. B세포 및 신호전달 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:400 |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | R.677.10 |
| Immunogen | Synthetic peptide corresponding to the amino-terminal sequence of human Lyn |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 16.7 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10981679 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with any other Src-family members.
Target Information
Lyn proto oncogene (Lcl/Yes related novel protein tyrosine kinase) is encoded by the Lyn gene located on chromosome 8 in humans and belongs to the Src family kinase. It is a non-receptor tyrosine kinase that acts as a mediator in transducing cellular signaling. Lyn is mainly expressed in hematopoietic cell types, including lymphoid and myeloid cells, but excluded in T lymphocytes. Lyn plays diverse roles such as in regulation of B cell receptor signaling, mast cell signaling, and Epithelial-Mesenchymal Transition (EMT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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