Thermo Fisher Scientific DKC1 Polyclonal Antibody
Thermo Fisher Scientific DKC1 Polyclonal Antibody는 인간 DKC1 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot과 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific DKC1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human DKC1. Recombinant protein control fragment (Product #RP-92002). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856023 |
Product Specific Information
Immunogen sequence:
EAGTYIRTLC VHLGLLLGVG GQMQELRRVR SGVMSEKDHM VTMHDVLDAQ WLYDNHKDES YLRRVVYPLE KLLTSHKRLV MKDSAVNAIC YGAKIMLPGV LRYEDGIEVN QEIVVIT
Target Information
This gene is a member of the H/ACA snoRNPs gene family. snoRNPs are involved in rRNA processing and modification and are classified into C/D and H/ACA families. The H/ACA snoRNPs include NOLA1, 2, and 3 proteins. The protein encoded by this gene and the NOLA proteins localize to nucleoli and nuclear coiled bodies. Depletion of any of these proteins impairs 18S rRNA production and pseudouridylation. These proteins are also components of the telomerase complex.
Mutations in this gene cause X-linked dyskeratosis congenita and Hoyeraal-Hreidarsson syndrome. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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