Thermo Fisher Scientific PIMT Polyclonal Antibody
PIMT 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 고순도의 액상 항체이며, PBS/glycerol buffer에 보관됩니다. 인체 및 생쥐 시료에 반응하며, 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 714–853 of human TGS1 (NP_079107.6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.72 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855892 |
Product Specific Information
Immunogen sequence:
RVIAIDIDPV KIALARNNAE VYGIADKIEF ICGDFLLLAS FLKADVVFLS PPWGGPDYAT AETFDIRTMM SPDGFEIFRL SKKITNNIVY FLPRNADIDQ VASLAGPGGQ VEIEQNFLNN KLKTITAYFG DLIRRPASET
Target Information
Catalyzes the two serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure.
The enzyme is specific for guanine, and N7 methylation must precede N2 methylation.
Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, colocalization with coilin, and formation of canonical Cajal bodies (CBs).
Plays a role in transcriptional regulation. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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