Thermo Fisher Scientific CHI3L1 Polyclonal Antibody
Human CHI3L1 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody. WB, IHC, ICC에 사용 가능하며, 항원 친화 크로마토그래피로 정제됨. 인간 시료 반응성, 동결 건조 형태로 제공되며 연구용 전용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–10 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL |
| Immunocytochemistry (ICC/IF) | 1.5–15 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Chitinase 3-like 1 (Tyr22–Thr383) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608882 |
Product Specific Information
- In direct ELISAs, approximately 15% cross-reactivity with recombinant mouse Chitinase 3-like 1 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Human cartilage glycoprotein 39 (GP-39), also known as YKL-40, is a glycoprotein secreted by articular chondrocytes, synoviocytes, and macrophages. Serum and synovial fluid GP-39 levels are elevated in inflammatory diseases and correlate with the degree of joint destruction in rheumatoid arthritis.
GP-39 is expressed in articular chondrocytes and synovial cells, as well as in liver, but is undetectable in muscle tissues, lung, pancreas, mononuclear cells, and fibroblasts.
GP-39 is a candidate autoantigen in rheumatoid arthritis and plays an important role in cellular response to environmental changes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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