Thermo Fisher Scientific Kallikrein 7 Polyclonal Antibody
인간 및 생쥐 반응성의 Kallikrein 7 폴리클로날 항체로, Western blot, IHC, IP에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 보존제 없이 동결건조 형태로 제공. 암 및 피부 관련 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL |
| Immunoprecipitation (IP) | 25 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Kallikrein 7 (Glu23–His252) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608648 |
Product Specific Information
- In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human KLK1, 3, 4, 5, 8, 9, 11, and 14 is observed.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Kallikreins are a subgroup of serine proteases with diverse physiological functions. Many kallikreins are implicated in carcinogenesis and may serve as biomarkers for cancer and other diseases.
The Kallikrein 7 gene is part of a cluster of fifteen kallikrein subfamily members on chromosome 19. Its enzyme is involved in the proteolysis of intercellular cohesive structures preceding desquamation, the shedding of the outermost epidermal layer.
Alternative splicing results in two transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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