Thermo Fisher Scientific ROR2 Polyclonal Antibody
ROR2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (IHC)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human ROR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720755 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
ROR2 (receptor tyrosine kinase-like orphan receptor 2) is a type I transmembrane protein belonging to the ROR subfamily of cell surface receptors. It is involved in early chondrocyte formation, cartilage, and growth plate development.
This protein is highly expressed during early embryonic development, with expression levels dropping around day 16 and remaining low in adult tissues.
Defects in ROR2 are associated with:
- Brachydactyly type B1 (BDB1): An autosomal dominant skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails.
- Robinow syndrome (RRS): A recessive skeletal dysplasia with limb bone shortening, spinal defects, brachydactyly, and facial dysmorphism.
The protein contains:
- 1 frizzled (FZ) domain
- 1 immunoglobulin-like C2-type domain
- 1 kringle domain
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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