Thermo Fisher Scientific Nogo Receptor Polyclonal Antibody
Thermo Fisher Scientific의 Nogo Receptor Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가진 Rabbit IgG 폴리클로날 항체입니다. Western blot 및 ICC/IF에 최적화되어 있으며, 액상 형태로 1 mg/mL 농도입니다. 신경 재생 및 축삭 성장 억제 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full-length Human Nogo Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C (short term); for long-term storage, keep at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2720756 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
NOGO (RTN4R) is a receptor for RTN4, OMG, and MAG. Its signaling mediates activation of Rho and downstream reorganization of the actin cytoskeleton. NOGO also mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult CNS. In addition, NOGO acts with RTN4 and LINGO1 to regulate neuronal precursor cell motility during cortical development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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