Thermo Fisher Scientific Glutaminase Recombinant Rabbit Monoclonal Antibody (6H5L15)
Glutaminase 단백질을 인식하는 재조합 토끼 단클론 항체로, WB 및 ICC/IF에 최적화되어 있습니다. 높은 특이성과 재현성을 제공하며, Protein A로 정제된 액상 형태입니다. 인간, 마우스, 랫드 시료에 반응하며 연구용으로 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 4 publications |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6H5L15 |
| Immunogen | Protein corresponding to Human GLS (aa 251–533) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633041 |
Product Specific Information
This antibody is predicted to react with Monkey, Rabbit, Rat, and Mouse.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone specific antibody DNA sequences from immunoreactive rabbits, followed by screening to select the best candidates for production.
Advantages include:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the larger rabbit immune repertoire
Target Information
Glutaminase is a phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. It is primarily expressed in the brain and kidney, playing an essential role in:
- Generating energy for metabolism
- Synthesizing neurotransmitter glutamate
- Maintaining acid-base balance in the kidney
Alternative splicing of the Glutaminase gene results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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