Thermo Fisher Scientific TrkA Polyclonal Antibody
Sheep 유래 다클론 항체로 TrkA 단백질 검출에 사용. Western blot 및 IHC에 적합하며, rat TrkA의 extracellular domain 펩타이드를 면역원으로 사용. 동결건조 형태로 제공되며, 재구성 후 안정성 향상을 위해 글리세롤 첨가 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:2,000 |
| Immunohistochemistry (IHC) | 1:300–1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the extracellular domain of rat TrkA |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10717053 |
Product Specific Information
- Glycerol (1:1) may be added for additional stability.
- Reconstitute in 100 µL of sterile water.
Target Information
NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system.
TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway.
The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes.
Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation, and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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