Thermo Fisher Scientific TRPM7 Polyclonal Antibody
TRPM7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 검증됨. 인간, 생쥐, 랫트 반응성. 동결건조 형태로 제공되며 장기 보관 시 -20°C 권장. 연구용으로만 사용 가능.
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Thermo Fisher Scientific TRPM7 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the 4th cytoplasmic loop of human TRPM7 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and mouse.
- Specificity: TRPM7.
Target Information
TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that mediate capacitative calcium entry into cells.
TRP-PLIK functions both as an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations, depolarizing cells and increasing intracellular calcium.
As a kinase, it phosphorylates itself and other substrates. The kinase activity is essential for channel function, dependent on intracellular ATP and verified by kinase mutants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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