Thermo Fisher Scientific TRPM2 Polyclonal Antibody
TRPM2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC에 사용 가능. 인간 시료 반응성. 합성 펩타이드를 면역원으로 사용. 동결건조 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the 3rd extracellular loop of human TRPM2 (TRPC7, LTRPC2) conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: TRPM2.
Target Information
TRPM2 belongs to the ion transport protein family, including sodium, potassium, and calcium ion channels.
These proteins possess six transmembrane helices, with the last two flanking a loop that determines ion selectivity.
TRPM2 is activated by oxidative stress and confers susceptibility to cell death.
It functions as a calcium-permeable cation channel regulated by intracellular ADP-ribose.
Several alternatively spliced transcript variants of the TRPM2 gene have been described, though their full-length nature is not fully known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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