Thermo Fisher Scientific UBXN2B Polyclonal Antibody
Thermo Fisher Scientific의 UBXN2B 폴리클로날 항체로 인간 UBXN2B 단백질을 인식합니다. IHC(P) 및 ICC/IF에 사용 가능하며 항원 친화 크로마토그래피로 정제되었습니다. PBS(40% 글리세롤) 용액 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human UBXN2B. Recombinant protein control fragment (Product # RP-100343) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649219 |
Product Specific Information
Immunogen sequence:
GEQERRSSGP RPPSARDLQL ALAELYEDEV KCKSSKSNRP KATVFKSPRT PPQRFYSSEH EYSGLNIVRP S
Antigen sequence identity:
- Mouse: 69%
- Rat: 75%
Target Information
UBXN2B (UBX domain-containing protein 2B), also known as NSFL1 cofactor p37 and p97 cofactor p37, is a 331 amino acid protein containing one UBX domain and one SEP domain.
UBXN2B is required for ER and Golgi biogenesis and plays a role in their maintenance during interphase and reassembly at the end of mitosis.
Through interaction with VCP, UBXN2B forms a complex with membrane fusion activity.
It acts as an adapter protein necessary for Golgi and endoplasmic reticulum biogenesis, requiring USO1-GOLGA2 tethering and BET1L, with VCPIP1 also involved.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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