
Thermo Fisher Scientific ARMER Polyclonal Antibody
Human ARMER 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, ER 스트레스 유도 세포사멸 연구에 적합. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ARMER. Recombinant protein control fragment (Product #RP-91178). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2638228 |
Product Specific Information
- Immunogen sequence: FGSNKWTTEQ QQRFHEICSN LVKTRRRAVG WWKRLFTLKE E
- Highest antigen sequence identity to orthologs: Mouse – 98%, Rat – 100%
Target Information
Apoptosis is a key process for normal development and tissue homeostasis, mediated by caspases leading to DNA degradation. ARMER, a novel integral ER-membrane protein, protects cells from ER stress-induced apoptosis by inhibiting caspase-9 activity. It is distinct from the inhibitor of apoptosis proteins (IAP) family and lacks baculoviral IAP repeat (BIR) domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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