Thermo Fisher Scientific Drosha Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human DROSHA(Accession Q9NRR4), corresponding to amino acid residues H899-M949. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DROSHA,uniProtId:Q9NRR4-1,ncbiNodeId:9606,antigenRange:899-949,antigenLength:1374,antigenImageFileName:PA5-103162_DROSHA_Q9NRR4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103162_DROSHA_Q9NRR4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2852532

Product Specific Information

Antibody detects endogenous levels of total RNase III Drosha.

Target Information

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.