Thermo Fisher Scientific SynGAP Recombinant Rabbit Monoclonal Antibody (8M2S9)
SynGAP 단백질을 표적으로 하는 Thermo Fisher의 재조합 토끼 단클론 항체로, Western blot과 ELISA에 적합합니다. 인간, 생쥐, 랫트 반응성이 있으며, 높은 특이성과 안정성을 제공합니다. 뇌 조직에서 SynGAP 연구용으로 최적화된 제품입니다.
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Thermo Fisher Scientific SynGAP Recombinant Rabbit Monoclonal Antibody (8M2S9)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8M2S9 |
| Immunogen | A synthetic peptide corresponding to amino acids 1244–1343 of human SynGAP (Q96PV0) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911851 |
Product Specific Information
- Positive test controls include: Mouse brain, Rat brain
- Immunogen sequence:
SEKRLRQQQA EKDSQIKSII GRLMLVEEEL RRDHPAMAEP LPEPKKRLLD AQERQLPPLG PTNPRVTLAP PWNGLAPPAP PPPPRLQITE NGEFRNTADH
Target Information
Synaptic Ras-GTPase activating protein (SynGAP) is a PDZ-domain interacting protein expressed almost exclusively in the brain. SynGAP is a major component of the postsynaptic density and associates with PSD-95 and NMDA receptors. Its Ras-GTPase activity is inhibited by phosphorylation by CaM kinase II, suggesting SynGAP functions as a negative regulator of MAP kinase activation in the absence of active NMDA receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: MA5-42710_SynGAP_Q96PV0-1_Rabbit_PDP.jpeg)
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