Thermo Fisher Scientific MAD2L1BP Recombinant Rabbit Monoclonal Antibody (7W8H1)
Thermo Fisher의 MAD2L1BP 재조합 토끼 단클론 항체(7W8H1)는 인간, 마우스, 랫트에 반응하며 WB, IHC, ELISA에 사용 가능. HEK293 세포 발현 시스템 기반, 고순도 친화 크로마토그래피 정제. 세포주 HeLa, HepG2에 대해 양성 대조 확인.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 7W8H1 |
| Immunogen | A synthetic peptide corresponding to amino acids 175–274 of human MAD2L1BP (Q15013) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.95 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911853 |
Product Specific Information
- Positive test controls include: HeLa, HepG2
- Immunogen sequence:
YSVDQSLSTA ACLRRLFRAI FMADAFSELQ APPLMGTVVM AQGHRNCGED WFRPKLNYRV PSRGHKLTVT LSCGRPSIRT TAWEDYIWFQ APVTFKGFRE
Target Information
The protein encoded by this gene was identified as a binding protein of MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1).
MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all kinetochores are attached to the spindle.
This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis.
Alternatively spliced transcript variants encoding distinct isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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