Thermo Fisher Scientific ARID1A Recombinant Rabbit Monoclonal Antibody (9D4J6)
ARID1A 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체. Western blot, IHC, ICC/IF, ELISA에 적합하며 다양한 종(Human, Mouse, Rat)에 반응. 고순도 Affinity Chromatography 정제, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9D4J6 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1204–1314 of human ARID1A (O14497) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911850 |
Product Specific Information
- Positive test controls include: PC-3
- Immunogen sequence:
SMTPNPGYQP SMNTSDMMGR MSYEPNKDPY GSMRKAPGSD PFMSSGQGPN GGMGDPYSRA AGPGLGNVAM GPRQHYPYGG PYDRVRTEPG IGPEGNMSTG APQPNLMPSN P
Target Information
This gene encodes a member of the SWI/SNF family, which includes proteins with helicase and ATPase activities involved in transcriptional regulation via chromatin remodeling.
The encoded ARID1A protein is part of the SNF/SWI complex, required for transcriptional activation of genes typically repressed by chromatin.
It contains a DNA-binding domain recognizing AT-rich sequences and a C-terminal domain that enhances glucocorticoid receptor-dependent transcription.
ARID1A confers specificity to the SNF/SWI complex and may recruit it to target genes through protein-DNA or protein-protein interactions.
Two transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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