Thermo Fisher Scientific CYP2A6/CYP2A7/CYP2A13 Polyclonal Antibody
인간 CYP2A6/CYP2A7/CYP2A13 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot에 최적화되어 있으며, 고순도 친화성 크로마토그래피로 정제됨. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CYP2A6/CYP2A7/CYP2A13 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CYP2A6 (Accession P11509), corresponding to amino acid residues S4–M54 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2818766 |
Product Specific Information
Antibody detects endogenous levels of total Cytochrome P450 2A6/7/13.
Target Information
The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems that metabolize the fatty acid arachidonic acid (AA) to regulators of vascular tone.
P450 enzymes are monooxygenase enzymes requiring co-factors such as NADPH and P450 reductase. Over 200 genes encode P450s.
Epoxygenases metabolize AA to epoxyeicosatrienoic acids (EETs), while omega-hydroxylases produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE).
In addition to fatty acid metabolism, P450s metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids, and rifampicin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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