Thermo Fisher Scientific NPR1 Polyclonal Antibody
NPR1 단백질을 특이적으로 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 마우스, 랫트 시료에 반응하며 고순도 Affinity Chromatography로 정제됨. PBS/glycerol buffer에 보관하며 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NPR1 (Accession P16066), corresponding to amino acid residues R439–V489 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818768 |
Product Specific Information
Antibody detects endogenous levels of total NPR1.
Target Information
Guanylyl cyclases catalyze the production of cGMP from GTP and are classified into soluble and membrane forms. Membrane guanylyl cyclases (GC-A to GC-F) act as cell-surface receptors with extracellular ligand-binding, transmembrane, and intracellular catalytic domains. GC-A and GC-B serve as receptors for natriuretic peptides (atrial and brain types). NPR1 is a membrane-bound guanylate cyclase functioning as the receptor for both atrial and brain natriuretic peptides (ANP and BNP).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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