Thermo Fisher Scientific Lubricin Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

PA3-130 detects lubricin in human samples.
It has been successfully used in Western blot procedures.
By Western blot, this antibody detects a ~64 kDa protein representing lubricin in human samples.

The PA3-130 immunogen is a synthetic peptide corresponding to residues I(19) Q Q V S S Q D L S(28)C of human Lubricin.
This polyclonal antibody has been referred to as JSCIQQ.
This peptide (Cat. # PEP-288) is available for use in neutralization and control experiments.

Target Information

Lubricin is a glycoprotein encoded by the PRG4 gene.
It functions as a component of joint lubrication and synovial homeostasis by reducing friction in joints and preventing synovial cell overgrowth.
Lubricin is a large, water-soluble molecule that acts as a carrier for insoluble surface-active phospholipid (SAPL).
Depletion of lubricin function has been associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), an arthritic-like autosomal recessive disorder.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.