Thermo Fisher Scientific PLP1 Polyclonal Antibody
Thermo Fisher Scientific의 PLP1 Polyclonal Antibody는 마우스 시료에서 proteolipid protein 검출에 사용됩니다. Western blot 및 ICC/IF에 최적화되어 있으며, -20°C에서 보관합니다. 비결합형 항체로, whole serum과 0.05% sodium azide를 포함합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:1,000 | View 3 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the C-terminal residues K(269) L M G R G T K(276) of PLP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2165785 |
Product Specific Information
PA3-151 detects proteolipid protein in mouse samples.
It has been successfully used in Western blot and immunocytochemistry procedures.
By Western blot, this antibody detects ~23–26 kDa proteins representing the proteolipid protein and the splice variant DM20 in adult mouse brain samples.
The PA3-151 immunogen is a synthetic peptide corresponding to the C-terminal residues K(269) L M G R G T K(276) of PLP.
Target Information
PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system.
It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival.
Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2.
Alternatively spliced transcript variants encoding distinct isoforms or having different 5′ UTRs have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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