Thermo Fisher Scientific STAT1 Monoclonal Antibody (OTI15H3), TrueMAB

Applications

• Western Blot (WB): 1:2,000
• Immunocytochemistry (ICC/IF): Assay-dependent

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform additional desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

STAT1 (Signal Transducers and Activators of Transcription 1) is a transcription factor activated by interferons (α, β, γ), EGF, PDGF, and IL6.
It regulates genes involved in cell growth, apoptosis, immune responses, and lipid metabolism.
STAT1 is phosphorylated by JAK tyrosine kinases and translocates to the nucleus to modulate gene transcription.
The STAT1 gene is located on chromosome 2, and two alternatively spliced transcript variants exist.
STAT1 activation occurs via multiple ligand families, including IFN, gp130, and receptor tyrosine kinases.

For Research Use Only. Not for use in diagnostic procedures or resale without authorization.

제품 이미지

(이미지 없음)