Thermo Fisher Scientific Phospho-MLK1/MLK2 (Thr312, Thr266) Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:100

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide sequence around phosphorylation site of threonine 312/266(A-G-T(p)-Y-A) derived from Human MLK1/2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MLK1/MLK2,uniProtId:P80192-1,ncbiNodeId:9606,antigenRange:264-268|310-314,antigenLength:1104,antigenImageFileName:PA5-37818_MLK1MLK2_P80192-1_Rabbit.svg,antigenImageFileNamePDP:PA5-37818_MLK1MLK2_P80192-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:MLK1/MLK2,uniProtId:Q02779-1,ncbiNodeId:9606,antigenRange:264-268|310-314,antigenLength:954,antigenImageFileName:PA5-37818_MLK1MLK2_Q02779-1_Rabbit.svg,antigenImageFileNamePDP:PA5-37818_MLK1MLK2_Q02779-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2554426

Product Specific Information

A suggested positive control for IHC is human brain tissue.

Target Information

MLK is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.