Thermo Fisher Scientific HIP2 Polyclonal Antibody
HIP2 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody로, WB 및 IHC(P) 실험에 적합합니다. 인간에 반응하며, 다른 종에서도 예측 반응합니다. 고순도 액상 형태로 안정적인 신호 검출을 제공합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HIP2 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (SWDVETATELLLSN) corresponding to the C-terminus amino acids of UBE2K (aa 187–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_10980306 |
Product Specific Information
- Predicted to react with bovine, canine, mouse, and porcine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 2,000.
Target Information
HIP2 (UBE2K) accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. It catalyzes the synthesis of Lys-48-linked polyubiquitin chains, mediating selective degradation of short-lived and abnormal proteins such as ER-associated misfolded proteins. Ubiquitinates huntingtin and may suppress apoptosis of lipid-bearing macrophages through p53/TP53 degradation. Involved in ubiquitination and proteolytic processing of NF-kappa-B and supports ubiquitination of NFKB1. During viral infections, it may participate in MHC class I heavy chain degradation and RB1 degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.