Thermo Fisher Scientific Human Bcl-10 Synthetic Peptide
Human BCL-10 단백질의 N-말단 15개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. PA5-19931 항체의 블로킹 펩타이드로 사용 가능하며, NF-κB 활성화 및 면역 반응 연구에 활용됩니다. 고순도 정제, 액상 형태로 제공됩니다.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids at the amino terminus of human BCL-10.
PEP-0056 can be used as a blocking peptide with polyclonal antibody PA5-19931.
Target Information
BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK.
BCL-10 acts as an adapter between the upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex and serves as a substrate for MALT1.
Mutations in the BCL-10 gene can lead to Immunodeficiency 37 or mucosa-associated lymphoid type lymphoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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