Thermo Fisher Scientific Human DR6 Synthetic Peptide
휴먼 DR6 단백질의 15개 아미노산 서열로 구성된 합성 펩타이드. PA5-19930 항체의 블로킹 펩타이드로 사용 가능. 액상 형태, 200 µg/mL 농도, PBS(pH 7.2) 및 0.1% BSA 포함. -20°C 보관 권장.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids of human DR6.
PEP-0055 can be used as a blocking peptide with polyclonal antibody PA5-19930.
Target Information
DR6 is widely expressed in human tissues and cell lines. The ligand for DR6 has not been identified. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor-6. Like TNF-R1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kappa-B and JNK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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