Thermo Fisher Scientific Human CD263 (TRAIL-R3) Synthetic Peptide
인간 CD263(TRAIL-R3) 단백질의 세포외 도메인 부위를 기반으로 한 합성 펩타이드. 항체 PA5-19932의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 제공되며, PBS 버퍼(pH 7.2, 0.1% BSA, 0.02% sodium azide) 내 보관. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 19 amino acids near the extracellular domain of human DcR1.
PEP-0057 can be used as a blocking peptide with polyclonal antibody PA5-19932.
Target Information
TRAIL-R3 (CD263) is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. It does not induce apoptosis and functions as an antagonistic receptor protecting cells from TRAIL-induced apoptosis. This gene is p53-regulated and DNA damage-inducible. Expression is observed in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to TRAIL-induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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