Thermo Fisher Scientific MCM7 Recombinant Rabbit Monoclonal Antibody (MCM7, 2832R)
MCM7 단백질을 인식하는 Thermo Fisher의 재조합 토끼 단클론 항체. Western blot과 IHC(P)에서 1–2 µg/mL 농도로 사용 가능. HEK293 세포에서 발현된 IgG 형식으로, Protein A/G 정제 및 PBS(pH 7.4)에 보존제 없이 제공. -20°C 이하 보관 권장.
- 카탈로그번호
- 4176-RBM7-P1ABX
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific MCM7 Recombinant Rabbit Monoclonal Antibody (MCM7, 2832R)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MCM7, 2832R |
| Immunogen | Recombinant human MCM7 protein fragment (aa195–319) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C or –80°C (preferred) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- For formalin-fixed tissues: Heat sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, then cool at room temperature for 20 minutes.
Target Information
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance (MCM) proteins essential for the initiation of eukaryotic genome replication. The hexameric MCM complex is a key component of the pre-replication complex (pre_RC) and participates in replication fork formation and recruitment of DNA replication-related proteins.
The MCM complex, including MCM2, 4, 6, and 7, exhibits DNA helicase activity and may function as a DNA unwinding enzyme. MCM7 also associates with cyclin D1-dependent kinase CDK4, which may regulate its interaction with the tumor suppressor protein RB1/RB.
Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.